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From: Faculty of 1000 ct=l >
To: Jeff Epstein <jeeproject®yahoo.com>
Subject: Faculty of 1000 Monthly Update - November 2010
Date: Tue, 16 Nov 2010 15:20:12 +0000
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2,F1000 Monthly Update
Evaluations Rankings Reports Posters Magazine Faculty November 2010
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Editor's Choice New this Month
Cell Biology: Biosensor
beacon 1,096
Spider silk protein is Evaluations added
main article used as a molecular
spring to measure tension 7
in cell adhesion. Articles that Change Clinical Practice
Hidden Jewel: Infection
2
Cell Biology: Gateway Immunology: Gut Articles with Dissents
plagues IQ?
to the cilium reactions
Fighting infections saps Paw on f1OOO.com
A cell's "for cilia only" Can gut bacteria
energy from developing
address label. influence arthritis?
brain. Current Issue
;latest issue
F1000 Features LQR
One on One: Genome
Blossoms
Pioneering genome cell
biologist Tont Misteli on
main article chromatin organization
and the most detailed 3-
D model of a eukaryotic
genome reported to date.
Driving Self-Recognition
Heads and Tales Cancer's Conversions Thought Experiment More titan 30,000 different proteins
Randall Moon has A process at the heart On Plasmids: Genome generated by one gene are part of an
looked to tadpoles and of gastrulation in the synthesis for the rest of entirely unexpected signaling
stem cells for clues about developing embryo us. Directed evolution of mechanism that guides growing neurons.
embryonic development may be a useful model entire genomes might not
and cell fate. Now he has for tumor progression. be the best way to Elemental Shortage
his eye on turning By Nancy Gavert and generate new function. The world is running out of cheap
Airi Ben-ZetEr. By Andrew Ellington. phosphorus, just as biologists are
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biology into therapy. By beginning to understand the role it plays
Karen Hopkin. in evolution and human health.
Life Sciences Salary Survey 2010
Ili middle advert Scientists are making the most of their
careers despite dropping salaries and
rising lab costs.
Top 7 Evaluated Articles
1 How cilia talk Naturally Selected
video preview image
Primary (non-motile) cilia use membrane proteins in their role as a
coordinator of the cell's signaling pathways. New findings show how a cilium David Nutt talks about his work at
retains those membrane proteins - a barrier at its base made up of proteins Imperial College studying the
called septins.
21 molecular underpinnings of
2 To stent or not? addiction.
A large randomized trial demonstrates that stenting and surgical clearing of Recommend a Free 30-day Trial
arteries are safe and equally effective ways of treating the narrowing of the to your Librarian
carotid arteries, called stenosis.
3 Diabetes dilemmas You can use our online form to send
your recommendation. Alternatively,
This clinical trial demonstrates that two popular high blood pressure drugs you may qualify for free access via
had no effect on progressive kidney damage, but did slow degeneration of the HINARI or Faculty Member
retina - two complications of Type 1 diabetes. sponsorship.
4 One path to obesity
The authors report a novel mechanism by which a high-fat diet can alter the
expression of a large number of obesity-associated genes, suggesting new
approaches to treating obesity and insulin resistance.
5 Coat structures
Crystallographic analyses of subunits of the COPI coat - a critical structure
for the transport of protein-filled vesicles from the Golgi back to the
endoplasmic reticulum - reveal similarities to two other major vesicle coats in
the cell, suggesting a common origin for this type of structural protein.
6 Sensing tension
This study demonstrates a molecular mechanism for how adherens junctions
- protein complexes that occur at cell-cell junctions in epithelial tissues -
sense and respond to mechanical forces in the cell.
7 Monitoring patients
Monitoring patients after surgery using pulse oximetry, which measures the
oxygenation of arterial blood, can improve patient outcomes and lower
overall health-care costs by reducing the number of emergency resuscitations
and trips to the intensive care unit.
This FI000 Top 7 is a snapshot of the highest-ranked articlesfront a 30-day
period in the previous month, described by The Scientist reporting team. See
also Top 7s in Neuroscience, Developmental Biology, Immunology, Cell
Biology, Hidden Jewels.
To see the latest rankings, visit http://F1000.comf
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F1000 Posters toR
Poster of the month
Neurological Disorders
An immunotherapeutic strategy targeting neurotoxicity of
tPA: A new hope for the treatment of stroke
iievaluated Macrez et al. Based on: International Symposium on
poster Neuroprotection and Neurorepair 2010.
Summary I Poster
View our latest submissions, including from the recent:
World Congress on Pain 2010
European Respiratory Society 2010 meeting
Human Proteome Organisation 2010 meeting
g'.&posit a poster
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