EFTA02705391.pdf

From: Faculty of 1000 Sent: Wednesday, October 9, 2013 4:33 PM To: [email protected] Subject: F1000 Nobel Prize winners and specially selected articles <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> To ensure you receive F1000 emails, add [email protected] <mailto:[email protected]> to your safelist. If this email is not displaying properly, please view in your usual browser <http://p4trc.emv2.com/HM?a=ENX7CqkWrP9- 8SA9MIUt6SPnGHxKLuf5u_cStGbSlw8WObBhOGSmpqVsje_HhdBmMIGB> . <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MKJt6SPnGHxKLuf4dfcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHQ> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> ADVERTISEMENT <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MICIt6SPnGHxKLuf4CvcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHR> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> chttp://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKJt6SPnGHxKLuf4C_cStGb5lw8WObBh0G5mpqVsje_HhdBmMIHW> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MKJt6SPnGHxKLuf4CPcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHX> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MKJt6SPnGHxKLuf4CfcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHU> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?arENX7CqkWrP9- 8SA9MI0t6SPnGHxlauf4DvcStGb5lw8WObBh0G5mpqVsje_HhdBmMIFIV> chttp://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> October 2013 <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Nobel Prizes 2013 awarded to F1000 Faculty Members <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Our congratulations to Randy Schekman <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MK.It6SPnGHxKluf4D_cStGb5lw8WObBh0G5mpqVsje_HhdBmMIHa> , one of the Heads of Faculty for Cell Biology <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MI0t6SPnGHxKLuf4DPcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHb> at F1000Prime, on being awarded the 2013 EFTA_R1_02095480 EFTA02705391 Nobel Prize in Physiology or Medicine <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKR6SPnGHxKluf4DfcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHY> . Our congratulations also go to Michael Levitt <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MK.It6SPnGHxKluf4AvcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHZ> , F1000Prime Faculty Member in Structural Biology <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKR6SPnGHxKLuf4A_cStGb5lw8WObBh0G5mpqVsje_HhdBmMIHe> , on receiving the 2013 Nobel Prize in Chemistry <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKJt6SPnGHxKluf4APcStGbSlw8WObBh0G5mpqVsje_HhdBmMIHf> . There are now nine Nobel Prize winners amongst the F1000Prime Faculty. <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MK.It6SPnGHxKluf4AfcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHc> By ReptOnlx (Own work) CC-BY-SA-3.0.2.5.2.0.1.0 (http://creativecommons.orelicenses/by-sa/3.0)1, via Wikimedia Commons. <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> F1000 Community: coming to a city near you? In September we announced <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MIUt6SPnGHxKLuf4BvcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHd> a rapidly growing schedule of presentations, panels, workshops and events for the rest of 2013. F1000 will be visiting many cities and universities worldwide — in the UK (Cambridge, Oxford, Edinburgh, Swansea and Lancaster), Europe (Zurich, The Hague) and USA (San Francisco, Charleston). Contact us <mailto:[email protected]> to organize an F1000 presentation at your institute. <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> In London, we will be welcoming local members of the F1000 Community to our inaugural meet-up event <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MIUt6SPnGHxKluf4B_cStGb5lw8WObBh0G5mpqVsje_HhdBmMIHi> — a free networking evening aimed at junior researchers. And, we are fast approaching the one-hundredth appointed F1000 Specialist <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MI0t6SPnGHxKLuf4BPcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHj> . F1000 Specialists are experienced users of F1000's services who work with us and our prestigious Faculty Members to help grow our community and develop our services in exchange for exciting rewards. Interested? Apply Online <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MIUt6SPnGHxKLuf4BfcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHg> . <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKR6SPnGHxKLuf4GvcStGb5lw8WObBhOGSmpqVsje_HhdBmMIHh> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> 1,394 recommendations <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKJt6SPnGHxKLuf4G_cStGb5lw8WObBhOGSmpqVsje_HhdBmMIHm> added in the past month. Below is a selection: <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Cellular Whodunnit <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MIUt6SPnGHxKLuf4GPcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHn> This paper reads like an exciting murder mystery as the authors track down some of the culprits responsible for the intracellular detection of Gram-negative lipopolysaccharides. Kayagaki N, Wong MT, Stowe IB, et al. Science 2013 Sep; 341:1246-9 <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Mini brains created in lab <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MK.It6SPnGHxKLuf4GfcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHk> 2 EFTA_R1_02095481 EFTA02705392 This ground-breaking paper used a 3D culture system that, for the first time, led to the creation of cerebral organoids consisting of discrete brain structures recapitulating a developing human brain. Lancaster MA, Renner M, Martin CA, et al. Nature 2013 Sep; 501:373-9 <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Stem-cell shortcuts <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9Mlat6SPnGHxlauf4HvcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHI> Do hematopoietic stem cells really have to go through a series of progenitor differentiation steps to produce blood cells? Apparently, not always. Yamamoto R, Morita Y, Ooehara J et al. Cell 2013 Aug; 154:1112-26 <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> F1000Prime Reports <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Open-access review journal <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MI0t6SPnGHxlauf4H_cStGloSlw8WObBh0G5mpqVsje_HhdBmMIHq> , reporting on the hottest topics. <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MIUt6SPnGHxKLuf4HPcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHr> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Human spermatozoa: revelations on the road to conception <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 85A9MIUt6SPnGHxKluf4HfcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHo> Older men can still be fathers, despite engendering more miscarriages, but their babies have a higher risk of health problems such as bipolar disease, autism, schizophrenia and epilepsy. F1000Prime Report by R. John Aitken <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MI0t6SPnGHxKluf4EvcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHp> . F1000Prime Rep 2013, 5:39 See all recent F1000Prime Reports. <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9Mlat6SPnGHxKLuf4E_cStGb5lw8WObBh0G5mpqVsje_HhdBmMIHu> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> chttp://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9M1W6SPnGHxKluf4EPcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHy> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Our innovative open access journal <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MK1t6SPnGHxKluf4EfcStGb5lw8WObBhOGSmpqVsje_HhdBmMIHs> offering rapid publication, open peer review and open data. Below is a selection of our latest peer reviewed articles: <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> REVIEW The effects of anaesthesia on the developing brain: a summary of the clinical evidence <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MK.It6SPnGHxKluf4FvcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHt> [v2; ref status: indexed, http://11000r.es/1my <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKR6SPnGHxKluf4F_cStGb5lw8WObBh0G5mpqVsje_HhdBmMIHy> I Published: 20 Aug 2013 Yu CK, Yuen VMY, Wong GT et al. F1000Research 2:166 <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> WEB TOOL 3 EFTA_R1_02095482 EFTA02705393 taxize: taxonomic search and retrieval in R <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKR6SPnGHxKluf4FPcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHz> Iv1; ref status: indexed, http://f1000r.es/lpv <http://p4trc.emv2.com/HS?arENX7CqkWrP9-8SA9MK.1t6SPnGHxKluf4FfcStGb5lw8W0bBhOGSmpqVsje_HhdBmMIHw> Published: 18 Sep 2013 Chamberlain SA, Sziics E F1000Research 2:191 <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> OBSERVATION ARTICLE A salp bloom (Tunicata, Thaliacea) along the Apulian coast and in the Otranto Channel between March-May 2013 <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MICIt6SPnGHxKLuf4KvcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHx> [v1; ref status: indexed, http://f1000r.es/lok <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MICIt6SPnGHALuf4K_cStGb5lw8WObBhOGSmpqVsje_HhdBmMIH2> Published: 10 Sep 2013 Boero F, Belmonte G, Bracale R et al. F1000Research 2:181 <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MK.It6SPnGHxKLuf4KPcStGb5lw8WObBh0G5mpqVsje_HhdBmMIH3> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> » Tips <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MIUt6SPnGHxKLuf4KfcStGb5lw8WObBh0G5mpqVsje_HhdBmMIHO> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> You can follow your favourite subject areas or store searches on F1000Research <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MICIt6SPnGHxKluf4LvcStGb5lw8WObBh0G5mpqVsje_HhdBmMIH1> . You can also track articles <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MIgt6SPnGHxKLuf4L_cStGb5lw8WObBhOGSmpqVsje_HhdBmMIH6> to keep on top of changes in your favourite papers, and sign up for table of contents alerts <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKJt6SPnGHxKLuf4LPcStGb5lw8WObBh0G5mpqVsje_HhdBmMIH7> if you would like to stay in the loop about all new articles. <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9M lUt6SPnGHxKLufillfcStGb5lw8WObBh0G5mpqVsje_HhdBm MIH4> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MIUt6SPnGHxKLuf4IvcStGb5lw8WObBhOGSmpqVsje_HhdBmMIHS> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> A comprehensive listing <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MICIt6SPnGHxKLuf4l_cStGb5lw8WObBh0G5mpqVsje_HhdBmMIH-> of clinical trial articles reviewed by the F1000 Faculty, with the most important tagged as recommended. <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Below is a taster of F1000Trials content. To read, please sign-in <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKR6SPnGHxKluf4IPcStGb5lw8WObBh0G5mpqVsje_HhdBmMIH_> or register for free <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MIUt6SPnGHxKLuf4IfcStGb5lw8WObBh0G5mpqVsje_HhdBmMIH8> : <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Gluten-free: facts, not fads <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKIt6SPnGHxKLuf4JvcStGb5lw8WObBh0G5mpqVsje_HhdBmMIH9> 4 EFTA_R1_02095483 EFTA02705394 This study presents the first controlled data on gluten avoidance in non-celiac patients; it adds at least some evidence- based medicine to all of the noise. Vazquez-Roque MI, Camilleri M, Smyrk T, et al. Gastroenterology 2013 May; 144:903-11.e3 <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Changes Practice: lung protective ventilation <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9Mlat6SPnGHxlauftl_cStGb5lw8WObBh0G5mpqVsje_HhdBmMIEC> This excellent paper hosts four Changes Clinical Practice recommendations: lung-protective ventilation is not just for acute lung injury patients, but rather lung protection begins in the operating room. Futier E, Constantin JM, Paugam-Burtz C et al. N Engl J Med 2013 Aug; 369:428-37 <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Cherry juice therapy for osteoarthritis? <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MIUt6SPnGHxKluftliPcStGb5lw8WObBh0G5mpqVsje_HhdBmMIED> A clinical trial in which individuals with knee osteoarthritis were randomized to receive either tart cherry juice or a placebo drink, with the cherry juice group demonstrating an overall positive response. Schumacher HR, Pullman-Mooar S, Gupta SR et al. Osteoarthr Cartil 2013 Aug; 21:1035-41 <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> chttp://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MIUt6SPnGHxKLuftlfcStGb5lw8WObBh0G5mpqVsje_Hhd8mMIEA> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Open Repository <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MK1t6SPnGHxKluf4OvcStGb5lw8W0b8h0G5mpqVsje_HhdBmMIEB> for posters and slide presentations; completely free to view and submit. Below is a selection: <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> NEUROSCIENCE <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> dittp://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKJt6SPnGHxlauf40_cStGb5lw8WObBh0G5mpqVsje_HhdBmMIEG> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Are all brains wired equally? chttp://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MIUt6SPnGHxKluf40PcStGb5lw8WObBh0G5mpqVsje_HhdBmMIEH> Koutra D, Gong Y, Ryman Set al. 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