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For Key Client Partner Clients or U.S. Institutional Investors. Not for
Retail Distribution
COMPANY OVERVIEW I JULY 2018
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The next breakthrough technology from the Link Group
1
Targeting the outpatient market with a novel MIS midline kit providing
physician procedural flexibility and efficiency
2
First of its kind affordable navigation system coupled with a unique,
highly engineered, portfolio of consumable products
3
Aligned with the future of healthcare:
better for the patient
better for the physician
better for the provider (facility)
4
Robust, capital-light growth model, validated by successful beta
launch, highly attractive gross margins, and existing reimbursement
5
Commercial-ready investment developed by the LINK Group who has a
proven track record
2
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1
Targeting the outpatient market with a novel MIS midline kit providing
physician procedural flexibility and efficiency
The transition to outpatient care
2015
2005
Outpatient
5%
Outpatient
45%
VCF
5%
2017 spinal device market opportunity
Other
13%
Traditional
41%
In patient
95%
In patient
55%
Interbody
22%
Efficiency of care will continue to drive cases to the outpatient setting
Degenerative spinal cases are increasingly being performed in ASCs
There has been a nine-fold increase in procedures performed in an
outpatient setting since 2005
IS midline spine surgery focus
r
ASC facilities and providers are keenly focused upon efficiency of care
given the reimbursement environment
MIS Midline techniques are suitable for the ASC environment given
he low morbidity associated with the procedure
Products that are well-engineered, simple, reproducible and that
rovide end-to-end MIS procedural solutions will win
11
1
The market needs the right product for the right setting; specifically an
unparalleled continuum of fusion implants that are applied according to
a patients pathology and surgical requirements and not a "one size fits
all" approach
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$8 billion globally (2% CAGR)
LinkSPINE currently addresses —60% of the spinal market or $5
billion annually
Biologics
19%
MidlineChoice platform
LINKSPINE's "MidlineChoice" platform of products positions the
company to not only participate in, but to define the relatively new
Midline Spine Surgery sector
MidlineChoice can be used for traditional and interbody spinal
procedures
f
MidlineChoice consists of a consolidated kit which offers versatile
reatment alternatives dependent upon the patients needs
Eliminates the need for excess inventory and is ideal for hospitals
and ASCs where storage space is limited
The MidlineChoice platform is aimed at the fastest growth areas of
the market: outpatient surgery, and the growing population of elderly
patients suffering from degenerative spine pathology
Note: LinkSPINE currently addresses the blue shaded areas in the charts above
Sources: Orthopedic Review, OrthoWorld, iData Research, Orthopedic Network
news
3
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2
First of its kind affordable navigation system coupled with a unique,
highly engineered, portfolio of consumable products
Spinal navigation
Spine navigation
5%
Spine
robotics
16%
Product
I The trend towards MIS techniques
has led to increased use of x-ray
in order to see the relevant
anatomy. Spine surgeons are
exposed to 50x more radiation
than hip surgeons
Standard of
Care
79%
—$2.5 billion in 2017
12% annual growth
I Navigation can reduce exposure
to physicians by 80-90%
H Navigation options are limited in
use in outpatient surgery given the
high cost of systems
LinkSPINE consumable products
Description
H Novel, inter-fixated device offers a compelling
alternative to conventional pedicle screws / rods
I Unique product designs create an effective,
economical operating room solution
H Specialized instruments to optimize delivery of
MIS two screw constructs
I Compact kit and straightforward technique
designed specifically for ASCs
I Powerful, versatile, and deep platform that can be
used in any degenerative lumbar fusion cases
I Offers intra-operative customization to match
patient anatomy and pathology
I User-friendly interface
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I Novel, chip-based software platform to
facilitate placement of screws
I Razor / blade model
I Drives strong customer adoption of
LinkSPINE's end-to-end MIS solutions
I Expected launch in 2H 2019
I Costs —10% of conventional navigation / robotics system
I ASP of typical navigation / robotics system is >$500,000
I Compact device specifically designed for outpatient centers / ASCs
I Activated with a pull tab and requires no change to surgical workflow
Unique to Market
Access
I Compact design for ASC application
I PLIF and TLIF cages manufactured out of unique,
roprietary blend of Hydroxyapatite & PEEK
f
I Early mover on an osteoconductive interbody
fusion device
I Comprehensive MIS access, decompression, and
disc preparation kit to facilitate safe, reproducible
outcomes
1
1
1
Commercial
1
1
Deep bench of best-in-class commercial products provides premium,
end-to-end solutions for minimally invasive midline surgeries
Early to Market
Note: MIS — Minimally Invasive Surgery; ASP — Average Selling Price; ASC
Ambulatory Surgical Center
4
MidlineChoice MidlineChoice
MidlineChoice
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3 Aligned with the future of healthcare
Better for patients
Better for physicians
I Reduced surgical time and lower radiation
exposure with TargetLlNK
H Minimally invasive surgery involves less
trauma to the patient, hence a faster
recovery
I Lower out of pocket costs to the patients
due to:
I Treatment in outpatient center / ASCs
cheaper than normal full-service
hospitals
IIShorter recovery times (no overnight
stay at hospitals, fewer
rehabilitation visits, etc.)
I Reduction in radiation exposure as
TargetLlNK can capture the required images
in 2 images, versus —50 x-rays in current
MIS spine procedures
I Shorter learning curve; open spine surgeons
often gain familiarity with MidlineChoice after
2-4 cases
I Surgeons may decide on the type of MIS
surgery intra-operatively as the kit provides
a full continuum of MIS options
I Faster surgeries allow physicians to see
more patients
Better for facilities
I TargetLlNK is an affordable and effective alternative versus robotics
I Minimally invasive surgery leads to shorter hospital stays or even
outpatient treatment
I Less storage space needed for the compact surgical kits and navigation
system
I No need to purchase extra inventory for a "just-in-case" situation as the
products are
interchangeable
5
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4
Robust capital-light growth model validated by successful beta launch,
highly attractive gross margins and existing reimbursement
llinkSPINE highlights
I
Successful US-beta launch with minimal sales activity, corroborated by
trong numbers in Europe
d
Strong gross margin on low volumes provide business flexibility and
owers the Company's cash burn
D
LinkSPINE's kit approach lowers the working capital requirements of a
raditional spine company
i
LinkSPINE's FDA-approved devices fit seamlessly to the existing
reimbursement pathway for lumbar fusion constructs
ll$25mm capital invested in LinkSPINE
H1'17
Lumbar spinal fusion reimbursements
$60
Cages alone
10%
Other
4%
Cages
and
l
screws
15%
Fusions in lumbar spine are most
often performed with cages and
screws or with only screws
LinkSPINE's FDA-approved product
platform addresses a combined 86%
f the lumbar fusion constructs
1
Screws
only
41%
In 2017, reimbursement varied from
—$9k to —$15k, providing ample
margin opportunity for LinkSPINE
$0
2017
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2018
2019
Sales
2020
2021
Gross margin
Note: General medical device company includes: Stryker, Hospira, Medtronic,
Becton Dickenson, Boston Scientific, J&J, Baxter; pure play spine companies
include Alphatec, SeaSpine,
K2M, Globus, NuVasive
6
2022
$30
$9.3
$0.8
$2.1
60%
H2'17
Revenue and gross margin
100%
H1'18
56
US LinkSPINE progress
Number of implantation cases utilizing LinkSPINE devices has approximately
doubled
from H1'17 to H1'18 despite having minimal commercial activity
110
90
89.5% 89.0%
87.8%
80%
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5
Commercial-ready investment developed by the LINK Group who has a
proven track record
(LINK Group
Global leader in orthopedics with a premium line of large joints and
custommade
solutions
Leading player in the Revision market
Complete in-house production from the liquid metal to the coated and
sterile-packed products
LINK Group is headquartered in Hamburg, Germany and founded by
aldemar Link in 1948
ri
Sale of SB Charite
Artificial Disc for $325
million plus future
ayments from ISI3
fl
Sale of Cervitech for
$80 million including
future payments from
NuVasive
Sale of the STAR
Ankle to SBI for an
ndisclosed amount
I
Stryker subsequently
acquired SBI in a
transaction up to $375
million
LINK has a proven track record
Engineering is LINK's key to success
(ley management
Technology driven company that is on the forefront of innovation for 70+
}ears
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Consistently the early mover in many orthopedic innovations
Efficient use of engineering resources — small teams with broad knowledge
and cooperation with key opinion leaders
Dennis Farrell
CEO, LinkSPINE
Helmut Link
Proprietor, Link Group
Norbert Ostwald
CEO, Link Group
Peter Willenborg
CFO, Link Group
Has been with LinkSPINE since 2011, serving as president since
2015 and previously leading Sales, Marketing and Product
Development initiatives
7
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Investment opportunity
Differentiated
Approved
Commercial
Reimbursed
Derisked
1
1
1
1
1
Proposed raise: $20-25mm
Investment proceeds will be used to:
Emerging player in the minimally invasive outpatient pain
market, focusing on the relatively infant "Midline" Spine
Surgery sector
Riding industry tailwinds of aging demographics, transition to
outpatient care settings, and strong focus on faster recovery
and risk-reduction
Strong track record with support from the LINK Group in terms
of industry and technological expertise, intellectual and
financial capital, commercial experience, and etc.
Build a robust commercial sales and marketing infrastructure
Deutsche Bank key contacts:
Expand geographically, specifically in the sun-belt states of Florida,
l eorgia, Texas, Arizona and California
I1
Hybrid distribution strategy to include direct representation and
partnership with independent agents that focus upon novelty
Launch, commercialize, and tightly integrate unique and low-cost
avigation system for maximized pull through of implant platform
ii
Continue to innovate highly-engineered novelty minimally-invasive
products
Seth Damergy
Managing Director
Global Head of Medical Technology
[email protected]
W: (212) 250-3284
M: (917) 292-2052
Benjamin Bible
Vice President
Healthcare, Medical Technology
[email protected]
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W: (212) 250-5264
M: (651) 343-6709
8
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Disclaimer
THIS PRESENTATION IS NOT AN OFFER OR SOLICITATION OF AN OFFER TO BUY OR SELL
SECURITIES. IT IS PROVIDED AS INFORMATION ONLY. THIS PRESENTATION DOES NOT
CONTAIN ALL OF THE
INFORMATION THAT IS MATERIAL TO AN INVESTOR. BY ATTENDING THE PRESENTATION
OR BY READING THE PRESENTATION SLIDES YOU AGREE TO BE BOUND AS FOLLOWS:
This document has been prepared by, and is the sole responsibility of
LinkSPINE Inc. ("Company" or "LinkSPINE"). It is confidential and contains
proprietary information and intellectual property belonging to LinkSPINE.
Such
information is solely for information purposes and is being furnished
through Deutsche Bank AG, acting through its New York Branch (and/or any of
its affiliates and/or branches) ("DB", the "Financial Adviser"). The
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This information is confidential and may not be excerpted from, summarized,
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Failure to comply with this restriction may constitute a violation of
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one else and, accordingly, will not be responsible to any other person for
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protections afforded to their respective clients or for advising any person
in relation to this document. Neither the receipt of this information by any
person, nor any information contained herein constitutes, or shall be relied
upon as
constituting the giving of investment advice by the Financial Adviser to any
such person. For the avoidance of doubt, the Financial Adviser has not acted
or is not acting (and does not purport to act in any way) in a fiduciary
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communications or inquiries related to the Company or the potential
transaction should be directed to the Financial Adviser. Under no
circumstances should the Company or any of its employees be directly
contacted in connection with
this information or your possible interest in any transaction contemplated
herein.
Although LinkSPINE believes reasonable efforts have been made to ensure the
accuracy of the information contained in this document, it may include
certain inaccuracies or typographical errors and may be changed or updated
later,
at the sole discretion of the Directors of the Company. This document is
intended for discussion purposes only and is provided without warranty of
any kind. No reliance should be placed on any information presented herein
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reliance is at your own risk. This document is not a prospectus for any
securities and does not constitute an offer or invitation for the sale or
purchase of any securities described herein and shall not form the basis of,
or be relied on in
connection with, any contract, commitment or investment decision in relation
thereto.
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The information set out herein is preliminary and should not be relied upon
to form the basis of any decision to acquire LinkSPINE or for any purpose.
LinkSPINE, the Financial Adviser and their respective directors, officers,
employees,
members, partners, shareholders, affiliates, agents, advisers and other
representatives (collectively, "Representatives") and their respective
contributors hereby disclaim all warranties (express and implied) and
conditions with regard to
this information and any and all sections of the document and the accuracy
or completeness of such information. The Financial Adviser and its
respective Representatives have not independently verified any of the
information
contained herein. Neither LinkSPINE nor the Financial Adviser nor any of
their respective Representatives assume any responsibility for the
independent verification of any information contained herein and have relied
on such
information being complete and accurate in all material respects, and
neither LinkSPINE nor the Financial Adviser nor any of their respective
Representatives undertake any obligation to keep any information presented
herein updated
or to provide recipients with access to any additional information; any
opinions may change without notice. Recipients should conduct their own
investigation and analysis of the Company, its business, prospects, results
of operations
and financial condition.
In no event shall LinkSPINE, the Financial Adviser or any of their
respective Representatives have any liability whatsoever including for any
direct, indirect, or consequential damages arising out of or in any way
connected with the
information contained herein or any omissions therefrom or the use of or
reliance on this document, whether based on contract, tort, negligence,
strict liability or otherwise. This presentation, if handed out at a
physical investor meeting
or presentation, should be returned promptly at the end of such meeting or
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you must return it immediately to the Company.
This presentation may include forward-looking statements that reflect the
Company's intentions, beliefs or current expectations. Forward-looking
statements involve all matters that are not historical by using the words
"may", "will",
"would", "should", "expect", "intend", "estimate", "anticipate", "target",
"believe" and similar expressions or their negatives. Such statements are
made on the basis of assumptions and expectations that the Company currently
believes
are reasonable, but such assumptions and expectations could prove to be
wrong. There can be no assurance that (i) the Company has correctly measured
or identified all of the factors affecting its business or the extent of
their likely
impact, (ii) the publicly available information with respect to these
factors on which the Company's analysis is based is complete or accurate,
(iii) the Company's analysis is correct or (iv) the Company's strategy,
EFTA01438120
which is based in part
on this analysis, will be successful. Forward -looking statements involve
numerous risks and uncertainties that could cause actual results to differ
materially and adversely from expected results. No attempt has been made by
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that any of these statements, projections or forecasts will come to pass or
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forecasted result will be achieved. Any forward-looking statements made by
or on behalf of the Company speak only as at the date of this presentation.
Save as required by any applicable laws or regulations, the Company
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no obligation publicly to release the results of any revisions to any
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in its expectations or to reflect events or circumstances after the date of
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Deutsche Bank AG is authorized under German Banking Law (competent
authority: European Central Bank) and, in the United States, by the Security
Exchange Commission It is subject to supervision by the European Central
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9
EFTA01438121
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0 2018 Deutsche Bank AG. All rights reserved. 027521 072018
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ℹ️ Document Details
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EFTA01438106
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