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From: Faculty of 1000
To: Jeff Epstein <[email protected]>
Subject: February update: Cells on standby - down but not out
Date: Tue, 08 Feb 2011 17:11:48 +0000
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;',F1000 Monthly Update
Evaluations Rankings Reports Posters Magazine Faculty February 2011
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Editor's Choice
New this Month
Down but Not Out
Cells on standby are 1,209
surprisingly busy. Hilary Evaluations added
Colter thinks they might
be busy protecting 5
themselves against Articles that Change Clinical Practice
oxidative damage. Art
F1000 Hidden Jewel. 14
Articles with an F1000 Factor of 11+
Current Issue
Microbiology: Physiology: Developmental
The Great Escape Time and Temperature Biology:
How a virus escapes from Body temperature resets Losers Fight Back ; 41atest issue
membrane vacuoles to circadian rhythms. How cells escape death
infect other cells. after a temporary
setback.
F1000 Features ;‘, top
Impure Genius
Lewis Cantley has
made a career of Face to Face with the Emotional
turning chemical Brain
contaminants into How the amygdala responds to facial
groundbreaking signals predicts both normal and
discoveries - including psychopathologic emotional states.
novel lipids, potent Ahmad R. Hariri & Paul J. Whalen
inhibitors, and kinases
involved in cancer. The Genes of Parkinson's Disease
Karen Hopkin The minority of Parkinson's cases now
known to have genetic origins are
shedding light on the cellular
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When Stress Is Good One on One: Parasites Do Fruit Flies Dream mechanisms of all the rest. Bobby
Fast blood flow protects Unite! of Electric Bananas? Thomas and M. Flint Beal
against atherosclerosis: Gabriele Sorci discusses Visualizing neuronal
implications for treatment. how invaders can band activity in small brains Opening a Can of Worms
Christina M. Warboys, together to more over four dimensions. A father's determination to help his son
Narges Amini, Amalia de effectively infect hosts. Bfitim Brembs resulted in an experimental treatment
Luca. and Paul C. Evans for autism that uses roundworms to
modulate inflammatory immune
responses. Bob Grant
;t2,
Naturally Selected
Top 7 Evaluated Articles t-)12
1 Immune response feeds parasite
Salmonella is able to outcompete resident gut microbes by deriving energy Sir lain Chalmers rips into clinical
from the inflammatory immune response that is supposed to combat the researchers for not understanding
pathogen. what is know, not stating clearly
what their research adds, and not
2 Lung disease drug kind to muscles publishing negative or
Patients with acute respiratory distress syndrome using a neuromuscular 'disappointing' results.
blocker are more likely than those on a placebo to survive 90 days, and show
no increase in muscle weakness-a common concern among doctors. Recommend a Free 30-day Trial
3 Making peace with gut flora to your Librarian
Dendritic cells in the gut have beta-catenin signaling turned on constantly in You can use our online form to send
order to subdue inflammation and keep immune cells tolerant to commensal your recommendation. Alternatively.
bacteria and food antigens, offering a potential therapeutic target for you may qualify for free access via
autoimmune diseases. HINARI or Faculty Member
Thermo dynamics sponsorship.
4
Plants and yeast may be able to sense temperature through histone-mediated
nucleosome rearrangements, which result in variations in gene expression,
posing a possible mechanism for response to temperature stress.
5 New function for noncoding RNAs
Long noncoding RNAs, previously known to silence expression of certain
genes. also play a role in gene activation.
6 Antibody action
Previously assumed to only act extracellularly, researchers show that
antibodies can fight viruses inside the cell as well.
7 Pain relief for the addicted
In opiate-dependent patients, pain relief is tough to achieve, but those who
received an N-methyl-d-aspartate receptor antagonist with anesthesia during
back surgery reported less pain and needed less morphine during recovery.
This F1000 Top 7 is a snapshot of the highest-ranked articles from a 30-day
period in the previous month. described by The Scientist reporting team. See
also Top 7s in Medicine, Neuroscience, Immunology.
To see the latest rankings. visit http://11000.com.
Reports i tiP
The latest peer-reviewed F1000 Reports articles, published in F1000's two
PubMed-indexed journals, are now available to view.
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Chemical signaling in The coming health
the gastrointestinal crisis: indirect health
tract effects of global
L. Caetano M. Antunes, climate change
Julian E. Davies and B. Samuel S. Myers and
Brett Finlay Aaron Bernstein
Screening for Is deep brain
pancreatic cancer: stimulation a
what can cyst fluid prospective "cure" for
analysis tell us? addiction?
Walter G. Park Wayne Hall and Adrian
Carter
F1000 Posters
Evaluated Poster of the Month
; .b,evaluated Neuroscience
poster Bilateral lesions of the subthalamic nucleus prevent
escalation of cocaine intake in rats
Cohen et al. Based on: Neuroscience 2010 meeting.
Evaluated by Trevor W Robbins, University of Cambridge. UK
Summary I Poster I Evaluation
View our latest submissions, including from the recent:
• Neuroscience 2010 meeting
• 5th Conference of the Hellenic Society for Computational Biology and
Bioinformafics
• 52nd American Society of Hematology (ASH) Annual Meeting and Exposition
r'2- posit a poster
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EFTA00671058
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