EFTA02362535.pdf

From: Faculty of 1000 <[email protected]> Sent: Thursday, January 17, 2013 3:13 PM To: [email protected] Subject: Happy New Year! Debating the role of disordered proteins in molecular recognition, and other interesting articles. <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> To ensure you receive emails from Faculty of 1000, add [email protected] <mailto:[email protected]> to your safelist. <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-85A9MKJYiEvnGHxKLVIuVfc5tGb5lw8WObBh0G5mpqVsje_Hhd8mMIF5> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> ADVERTISEMENT <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> F1000 Prime <http://p4trc.emv2.com/H5?a=ENX7CqkWrP9- 85A9MIUYiEvnGHxKLVluavcStGb5lw8WObBh0G5mpqVsje_Hhd8mMIF-> F1000 Trials <http://p4trc.emv2.com/H9a=ENX7CqkWrP9-85A9MKJYiEvnGHxKLVlua_cStGb5lw8WObBh0G5mpqVsje_Hhcl8mMIF_> F1000 Research chttp://p4trc.emv2.com/H5?a=ENX7CqkWrP9- 85A9MIOYiEvnGHxKLVluaPcStGb5lw8W0b8h0G5mpqVsje_Hhd8mMIF8> F1000 Posters <http://p4trc.emv2.com/H5?a=ENX7CqkWrP9-85A9MKJYiEvnGHxKLVluafcStGb5lw8W0b8h0G5mpqVsje_HhdBmMIF9> Having trouble? View in your browser. <http://p4trc.emv2.com/HM?a=ENX7CqkWrP9- 85A9MIOYiEvnGHxKLVIrlfcStGb5lw8W0b8h0G5mpqVsjejihd8mMILA> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/H5?a=ENX7CqkWrP9-85A9MKJYiEvnGHxKLVIubvcStGb5lw8W0b8h0G5mpqVsje_HhdBmMIKC> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> January 2013 <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> F1000's faculty of over 5,000 expert scientists and clinical researchers, assisted by 5,000 associates, recommend the best articles in the life sciences. 1,414 recommendations were added in the last month, and you can see them all here <http://p4trc.emv2.com/H5?a=ENX7CqkWrP9-85A9MKJYiEvnGHxKLVIub_c5tGb5lw8W0b8h0G5mpqVsje_Hhd8mMIKD> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> EFTA_R1_01355438 EFTA02362535 <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MICIYiEvnGHxKLVIubPcStGb5lw8WObBh0G5mpqVsje_HhdBmMIKA> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Some of the articles that caught the attention of our F1000 Faculty this month. <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Mystery solved <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKJYiEvnGHxKLVIubfcStGb5lw8WObBh0G5mpqVsje_HhdBmMIKB> The long-standing immunological puzzle of which ligands bind to the MR1 receptor is elegantly elucidated, showing how careful monitoring of experimentation can pave the way to major discoveries. <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Another mystery solved <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MIOYiEvnGHxKLVIuYvcStGb5lw8WObBhOGSmpqVsje_HhdBmMIKG> Namely, how P14P is made in the plasma membrane of mammalian cells. <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Ready, set, go! <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKJYiEvnGHxKLVIuY_cStGb5lw8WObBh0G5mpqVsje_HhdBmMIKH> The authors provide some key insights into the early events in cellular reprogramming. chttp://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Ironing out the problem <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MIOYiEvnGHxKLVIuYPcStGb5lw8WObBh0G5mpqVsje_HhdBmMIKE> A surprising new finding that low iron levels may actually accelerate H. pylori-induced carcinogenesis. <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Mother (Nature) knows best? <http://p4trc.emv2.com/HS?aa•ENX7CqkWrP9- 8SA9MIOYiEvnGHxKLVIuYfcStGb5lw8WObBhOGSmpqVsje_HhdBmMIKF> Will Resveratrol and green tea extract prove successful in treating endometriosis symptoms? <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Education incentive? <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MIOYiEvnGHxKLVIuZvcStGb5lw8WObBhOGSmpqVsje_HhdBmMIKK> Higher education appears to have a protective effect against cell ageing (telomere shortening) in African Americans. <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> See all new recommendations» <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKJYiEvnGHxKLVIuZ_cStGbSlw8WObBh0G5mpqVsje_HhdBmMIKL> <http://webr.emv2.com/faculty1000/F1000Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MIOYiEvnGHxKLVIuZPcStGbSlw8WObBh0G5mpqVsje_HhdBmMIKI> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> This month our F1000Reports journals published a pair of open access articles that argue opposing sides of the debate on whether protein recognition can occur in the absence of stable structure. The articles, written by leaders in the field, have clear implications for protein engineering. <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MIUYiEvnGHxKLVIuZfcStGbSlw8WObBh0G5mpqVsje_HhdBmMIKJ> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Protein flexibility, not disorder, is intrinsic to molecular recognition <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9M lOYiEvnGHxKLVluevcStGb5lw8WObBh0G5mpqVsje_HhdBm MIKO> F1000 Report by Joel Janin <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKNiEvnGHxKLVlue_cStGb5lw8WObBh0G5mpqVsje_HhdBmMIKP> and Michael J.E. Sternberg chttp://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MIUYiEvnGHxKLVluePcStGb5lw8WObBh0G5mpqVsje_HhdBmMIKM> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> 2 EFTA_R1_01355439 EFTA02362536 <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MIUYiEvnGHxKLVluefcStGb5lw8W0bBhOG5mpqVsje_HhdBmMIKN> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> The case for intrinsically disordered proteins playing contributory roles in molecular recognition without a stable 3D structure <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MIOYiEvnGHxKLVIufvcStGb5lw8W0bBhOG5mpqVsje_HhdBmMIKS> F1000 Report by Vladimir N. Uversky <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKNiEvnGHxKLVIuf_cStGb5lw8W0bBhOG5mpqVsje_HhdBmMIKT> and A. Keith Dunker chttp://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MKJYiEvnGHxKLVIufPcStGlaSlw8W0bBhOG5mpqVsje_HhdBmMIKQ> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> See all new Reports» <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MIUYiEvnGHxKLVIuffcStGb5lw8W0bBhOG5mpqVsje_HhdBmMIKR> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> chttp://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> chttp://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MIUYiEvnGHxKLVIucycStGb5lw8W0bBhOG5mpqVsje_HhdBmMIKW> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> ADVERTISEMENT <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Also from Faculty of 1000 <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MIUYiEvnGHxKLVIuc_cStGb5lw8W0bBhOG5mpqVsje_HhdBmMIKX> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Open Repository <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MIUYiEvnGHxKLVIucPcStGb5lw8W0bBhOG5mpqVsje_HhdBmMIKU> for posters and slide presentations. <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Poster of the month -- Women's Health <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKJYiEvnGHxKLVIucfcStGbSlw8W0bBhOGSmpqVsje_HhdBmMIKV> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MKJYiEvnGHxKLVIudycStGb5lw8W0bBhOG5mpqVsje_HhdBmMIKa> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Effects of pregnancy on the speaking voice <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKNiEvnGHxKLVIud_cStGb5lw8W0bBhOG5mpqVsje_HhdBmMIKb> Zubaer S et al. <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Presented at EMPOWER 2012 - Empower International Medical Congress, 4 - 7 Sep 2012, P000 chttp://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MIUYi EvnGHxKLVIudfcStGb5lw8W0bBhOGSmpqVsje_HhdernMIKZ> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Browse all posters » <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKJYiEvnGHxKLVIuCycStGb5lw8W0bBhOG5mpqVsje_HhdBmMIKe> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> 3 EFTA_R1_01355440 EFTA02362537 <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MKNiEvnGHxKLVIuC_cStGb5lw8W0bBhOG5mpqVsje_HhdBmMIKI> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> RESEARCH ARTICLE Biased under-reporting of research reflects biased under-submission more than biased editorial rejection <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-85A9MICIYiEvnGHxKLVIuCPcStGb5lw8W0bBhOG5mpqVsje_HhdBmMIKc> (v1; ref status: Indexed, http://f1000r.es/VilqTX <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MK.IYiEvnGHxKLVIuCfcStGb5lw8W0bBhOG5mpqVsje_HhdBmMIKd> ) <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Published: 2 Jan 2013 <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> lain Chalmers, Kay Dickersin. F1000Research 2:1 <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> F1000Research has now come out of beta <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 8SA9MKJYiEvnGHxKLVIuDvcStGb5lw8W0bBhOG5mpqVsje_HhdBmMIKi> and is now approved chttp://p4trc.emv2.com/HS?a=ENX7CqkWrP9-85A9MIUYiEvnGHxKLVIuD_cStGb5lw8W0bBhOG5mpqVsje_HhdBmMIKj> for listing in PubMed. Publish by this time next week: view our author guidelines <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9- 85A9MKIYiEvnGHxKLVIuDPcStGb5lw8W0bBhOG5mpqVsje_HhdBmMIKg> and submit now to [email protected] <mailto:[email protected]> for rapid, hassle-free publication. <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> 1,414 recommendations added on F1000 Prime last month <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Anesthesiology & Pain Management (77) • Cardiovascular Disorders (53) • Cell Biology (365) • Chemical Biology (159) • Critical Care & Emergency Medicine (52) • Dermatology (33) • Developmental Biology (129) • Diabetes & Endocrinology (67) • Ecology (62) • Gastroenterology & Hepatology (63) • Genomics & Genetics (245) • Hematology (39) • Immunology (111) • Infectious Diseases (72) • Microbiology (150) • Nephrology (24) • Neurological Disorders (75) • Neuroscience (152) • Oncology (82) • Opthalmology (28) • Otolaryngology (32) • Pharmacology & Drug Discovery (248) • Physiology (226) • Plant Biology (50) • Psychiatry (70) • Public Health & Epidemiology (67) • Research Methodology (16) • Respiratory Disorders (74) • Rheumatology & Clinical Immunology (53) • Structural Biology (166) • Urology (33) • Women's Health (73) <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Browse all recommendationso <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MKJYiEvnGHxKLVIuDfcStGb5lw8W0bBhOG5mpqVsje_HhdBmMIKh> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HSL?lang=us&a=ENX7CqkWrP9- 8SA9MKJYiEvnGHxKU3zyvcStGb5lw8W0bBhOG5mpqVsje_HhdBmMId4> chttp://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> 4 EFTA_R1_01355441 EFTA02362538 <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> F1000Research is out of beta! <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> <http://p4trc.emv2.com/HS?a=ENX7CqkWrP9-8SA9MICIYiEvnGHxKLVIuAvcStGb5lw8WObBh0G5mpqVsje_HhdBmMIKm> Following a successful beta-phase, F1000Research has launched a new site, hosted on a new platform, with a new color. 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