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assn.org/cgi/content/abstract/171/ 21/ 1879?maxtoshow=&hits=10&RESULTFOR
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INTERNALci MEDICINE
Vol. 171 No. 21, November 28, 2011
Original Investigation
HEALTH CARE REFORM
National Performance on Door-In to Door-Out Time Among
Patients Transferred for Primary Percutaneous Coronary
Intervention
leph Herrin, PhD; Lauren E. Miller, MS; Dima F. Turkmani, MPH, MBA; Wato Nsa, MD, PhD;
Elizabeth E. Drye, MD, SM; Susannah M. Bernheim, MD, MHS; Shari M. Ling, MD; Michael T.
Rapp, MD, JD; Lein F. Han, PhD; Dale W. Bratzler, DO, MPH; Elizabeth H. Bradley, PhD;
Brahmajee K. Nallamothu, MD, MPH; Henry H. Ting, MD, MBA; Harlan M. Krumholz, MD, SM
Arch Intern Med. 2011;171(21):1879-1886. doi:10.1001/archinternmed.2011.481
Background Delays in treatment time are commonplace for patients with ST-segment
elevation acute myocardial infarction who must be transferred to another hospital for
percutaneous coronary intervention. Experts have recommended that door-in to door-out
(DIDO) time (ie, time from arrival at the first hospital to transfer from that hospital to the
percutaneous coronary intervention hospital) should not exceed 30 minutes. We sought to
describe national performance in DIDO time using a new measure developed by the Centers
for Medicare & Medicaid Services.
Methods We report national median DIDO time and examine associations with patient
characteristics (age, sex, race, contraindication to fibrinolytic therapy, and arrival time) and
hospital characteristics (number of beds, geographic region, location [rural or urban], and
number of cases reported) using a mixed effects multivariable model.
Results Among 13 776 included patients from 1034 hospitals, only 1343 (9.7%) had a
DIDO time within 30 minutes, and DIDO exceeded 90 minutes for 4267 patients (31.0%).
Mean estimated times (95% CI) to transfer based on multivariable analysis were 8.9 (5.6-
12.2) minutes longer for women, 9.1 (2.7-16.0) minutes longer for African Americans, 6.9
(1.6-11.9) minutes longer for patients with contraindication to fibrinolytic therapy, shorter
for all age categories (except >75 years) relative to the category of 18 to 35 years, 15.3
(7.3-23.5) minutes longer for rural hospitals, and 14.4 (6.6-21.3) minutes longer for
hospitals with 9 or fewer transfers vs 15 or more in 2009 (all P < .001).
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Conclusion Among patients presenting to emergency departments and requiring transfer
to another facility for percutaneous coronary intervention, the DIDO time rarely met the
recommended 30 minutes.
Author Affiliations: Section of Cardiovascular Medicine, Department of Internal Medicine,
Yale University School of Medicine, New Haven, Connecticut (Drs Herrin, Drye, and
Krumholz); Health Research and Educational Trust, Chicago, Illinois (Dr Herrin); Oklahoma
Foundation for Medical Quality, Oklahoma City (Drs Nsa and Bratzler and Mss Miller and
Turkmani); Taybah for Healthcare Consulting, Dallas, Texas (Ms Turkmani); Center for
Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven (Drs Drye,
Bemheim, and Krumholz); Centers for Medicare & Medicaid Services, Baltimore, Maryland
(Drs Ling, Rapp, and Han); Section of Emergency Medicine, George Washington University
School of Medicine and Health Sciences, Washington, DC (Dr Rapp); Oklahoma University
Health Sciences Center, College of Public Health, Oklahoma City (Dr Bratzler); Section of
Health Policy and Administration, Yale School of Public Health, and the Robert Wood
Johnson Clinical Scholars Program, Department of Internal Medicine, Yale University School
of Medicine, New Haven (Drs Bradley and Krumholz); The Veterans Affairs Ann Arbor Health
Services Research and Development Center of Excellence, and the Division of
Cardiovascular Medicine and Center for Healthcare Outcomes and Policy, University of
Michigan Medical School, Ann Arbor (Dr Nallamothu); and Knowledge and Encounter
Research Unit, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota (Dr
Ting). Ms Turkmani was employed by Yale University at the initiation of the project that led
to this publication.
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