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From: Joichi Ito
Sent: Saturday, June 6, 2015 2:35 PM
To: Jeffrey Epstein
Subject: Re: Direct Germans
Can I call you from the car in 1 hr?
> On Jun 6, 2015, at 10:31 AM, Jeffrey E. <[email protected]> wrote:
> 212 772 9416
> On Sat, Jun 6, 2015 at 10:24 AM, Joichi Ito < > wrote:
> I again feel like maybe I need to study math. I only know enough to =escribe non-messy things. How do I start?
> On Jun 6, 2015, at 10:22 AM, Jeffrey E. <[email protected]> =rote:
>>
> math is a notation that tries to describe messiness. the more =olistic. shape. mouthiness. is a more elegant way of
descrining =ertain concepts and mouthiness for a characteristic of food ( temp =hewiness. tastes )
>>
> On Sat, Jun 6, 2015 at 10:11 AM, Joichi Ito wrote:
> Turns out membrane proteins are also amazing molecules for color =A6 colors of light change their geometry which
our nerves can sense. =t's interesting how color goes from light -> molecular geometry =hange -> electrical energy in
neuron -> shapes in visual cortex -> =hapes in our brain.
>>
» Sorry, I'm still at the wrong scale, but...
>>
> > The math part is interesting. How do you think neurons and biology =ap onto our brain? Brains seem pretty messy
compared to math.
>>
» - Joi
>>
> > On Jun 6, 2015, at 9:49 AM, Jeffrey E. <[email protected]> =rote:
>> >
> » ive had a lot of back and forth with chomsky . the description =f some of these things that category theory helps
frame is really =eautiful. . coherence, is a pretty and contiguous shape, =ymmetries. make it both simple and
complex. . taking the donut and =wisting it into a know changes its topology and mathematics. Im =fraid I can begin
to make the case for feng shui, . doesn't make me =appy but it can be organized into a symphony of light modulated
inputs. =. ( I know its sounds a but woo woo. but it has serious math behind =t.
>> >
> > On Sat, Jun 6, 2015 at 9:39 AM, Joichi Ito wrote:
> > Maybe this is too microscopic, but Ed's work on =round-truthing science - the physics behind the biology and
=huguang's work in understanding membrane proteins will probably =elp us understand cellular communication
including the use of proteins =nd possibly other forces like magnetics and electrical and more crazy =hings.
>> >
> » I was remember the picture you had about the cells communicating =s an model of "pricing" of "value". The =hing
is that the cells communicate and transact using proteins that =nteract with cells via membrane proteins. We have only
discovered 500 =embrane proteins so far and the human genomes encodes for 8000 of which =e only have discovered
20. I'm not positive, but I think =nderstanding these membrane proteins will unlock a bunch of really =nteresting
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networks of communication both in the brain and between =uman beings that we don't understand yet. Shughuang has
part of =he key, which is a way to identify these non-water soluble proteins =sing what is called a QTY conversion. Not
sure if you're =nterested, but when we meet next, I should sit down and explain it to =ou if you don't already know. It's
pretty fascinating. =n addition to figuring out how cells signal and how the networks of =roteins in our body work /
environment work, this also unlocks many of =he secrets to smells.
>> >
> > I din't know this but it turns out that we have 5-10 =ifferent
> > membrane proteins per "odorant" that detects =ittle parts of the
> > bigger odorant molecule and they do this very fast. =ach membrane
> > protein senses part of the structure and they create an
> » =eurological signal based on this pattern and we figure out the
> » smell =A6
>> >
> » And the company we invested in, O2H is called O2H because the key =o understanding membrane proteins is to
make the non-water-soluable =embrane proteins, water-soluable by converting the certain amino acids =hich retains the
structure but changes the solubility so O2H is sort of =E2 water reversed". O2H has all of the commercialization =ights
to this field of study.
>> >
> > But... more broadly...
>> >
> > there is one sort of random "sense"... it =urns out that we have a cluster of nerves in our optic nerve that only
=ense blue light that sets our circadian. That's why they say =lue light affects mood and jet lag. These nerves have
nothing to do =ith the nerves that we "see" with.
>> >
> » We know for a fact that magnetics and electrical signals affect =he brain so I'm sure we can "sense" these.
>> >
> » Have you heard of people who put super-magnets in their fingers to =ense metal?
>> >
> » =ttp://io9.com/what-you-need-to-know-about-getting-magnetic-finger
> > -imp-813=37993
>>>
> > Tenzin would probably have some good thoughts on this.
>> >
> > I also have a very smart guy who is trying to convince me that =his works:
>> >
> > > http://tinyurl.com/qfoafft
>>>>
> > http://tinyurl.com/nv8thk6
>>>
> » - Joi
>> >
> > > On Jun 6, 2015, at 8:49 AM, Jeffrey E. <[email protected]> =rote:
>> >
> > > my question , for today is how many senses to we really have.? = what are their ranges. do we sense infrared.
without awareness. . =torm brewing etc.
>>>>
> > > On Sat, Jun 6, 2015 at 8:45 AM, Joi Ito rote:
> > » I remember Martin asking me some question a out w y sians =on't say answer things directly.
>> >>
> > » Here's sort of an answer to the opposite question. :-)
>> >>
> > > > » =ttp://www.quora.com/Why-are-Germans-so-nosey/answer/Yves-Gra
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> > > > » nger
>>»
»» -Joi
>>»
>>»
>>»
>>»—
>> » please note
> > > > The information contained in this communication is confidential,
> > » may be attorney-client privileged, may constitute inside
> > » information, and is intended only for the use of the addressee.
>> » It is the property of JEE Unauthorized use, disclosure or
> > » copying of this communication or any part thereof is strictly
> > > > prohibited and may be unlawful. If you have received this
»» communication in error, please notify us immediately by return
> > » e-mail or by e-mail to [email protected], and destroy this
>> » communication and all copies thereof, including all attachments.
> > » copyright -all rights reserved
>»
>»
>»
>»
>» —
>» please note
»>The information contained in this communication is confidential,
»> may be attorney-client privileged, may constitute inside
> » information, and is intended only for the use of the addressee. It
> > > is the property of JEE Unauthorized use, disclosure or copying of
> > this communication or any part thereof is strictly prohibited and
> » may be unlawful. If you have received this communication in error,
> » please notify us immediately by return e-mail or by e-mail to
> > [email protected], and destroy this communication and all
> » copies thereof, including all attachments. copyright -all rights
> » reserved
»--
>> please note
> > The information contained in this communication is confidential, may
» be attorney-client privileged, may constitute inside information,
> and is intended only for the use of the addressee. It is the
» property of JEE Unauthorized use, disclosure or copying of this
> communication or any part thereof is strictly prohibited and may be
» unlawful. If you have received this communication in error, please
» notify us immediately by return e-mail or by e-mail to
> [email protected], and destroy this communication and all copies
> thereof, induding all attachments. copyright -all rights reserved
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> --
> please note
> The information contained in this communication is confidential, may
> be attorney-client privileged, may constitute inside information, and
> is intended only for the use of the addressee. It is the property of
> JEE Unauthorized use, disclosure or copying of this communication or
> any part thereof is strictly prohibited and may be unlawful. If you
> have received this communication in error, please notify us
> immediately by return e-mail or by e-mail to [email protected],
> and destroy this communication and all copies thereof, including all
> attachments. copyright -all rights reserved
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